Azetidine, 3-(methylsulfonyl)- - Names and Identifiers
Azetidine, 3-(methylsulfonyl)- - Physico-chemical Properties
Molecular Formula | C4H9NO2S
|
Molar Mass | 135.18 |
Density | 1.29±0.1 g/cm3(Predicted) |
Boling Point | 320.1±31.0 °C(Predicted) |
pKa | 8.14±0.40(Predicted) |
Storage Condition | 2-8°C |
Azetidine, 3-(methylsulfonyl)- - Introduction
3-Methanesulfonyl-azetidine (3-Methanesulfonyl-azetidine), also known as MSA, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
1. Appearance: colorless liquid
2. molecular formula: C4H9NO3S
3. Molecular weight: 147.18g/mol
4. melting point:-17 ℃
5. Boiling point: 95-98 ℃
6. Soluble in water and organic solvents
7. Stable at room temperature
Use:
1. MSA is widely used in a variety of reactions in organic synthesis, such as nucleophilic substitution reactions and cyclization reactions.
2. It is also used as pharmaceutical intermediates and chemical reagents.
3. MSA can also be used to synthesize biologically active compounds.
Method:
The commonly used method for preparing MSA is to prepare by sulfonation on the ring of azetidinone. The specific steps include reacting azetidinone with methanesulfonyl chloride under base catalysis to generate MSA.
Safety Information:
1. MSA may be irritating to the skin and eyes, so you should pay attention to the use of personal protective equipment during operation and contact.
2. Avoid inhaling its vapor and ensure that it is used in a well-ventilated area.
3. should be stored away from the fire and oxidant.
4. Refer to the relevant Chemical Safety Data Sheet (MSDS) for specific safety information on the use and handling of MSA.
Last Update:2024-04-10 22:29:15